Characterization of genome-wide TFCP2 targets in hepatocellular carcinoma: implication of targets FN1 and TJP1 in metastasis

BACKGROUND: Transcription factor CP2 (TFCP2) is overexpressed in hepatocellular carcinoma(HCC) and correlated with the progression of the disease. Here we report the use of an integrated systems biology approach to identify genome-wide scale map of TFCP2 targets as well as the molecular function and...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Xu, Xiao, Liu, Zhikun, Zhou, Lin, Xie, Haiyang, Cheng, Jun, Ling, Qi, Wang, Jianguo, Guo, Haijun, Wei, Xuyong, Zheng, Shusen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311423/
https://ncbi.nlm.nih.gov/pubmed/25609232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0121-1
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