Characterization of genome-wide TFCP2 targets in hepatocellular carcinoma: implication of targets FN1 and TJP1 in metastasis

BACKGROUND: Transcription factor CP2 (TFCP2) is overexpressed in hepatocellular carcinoma(HCC) and correlated with the progression of the disease. Here we report the use of an integrated systems biology approach to identify genome-wide scale map of TFCP2 targets as well as the molecular function and...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Xu, Xiao, Liu, Zhikun, Zhou, Lin, Xie, Haiyang, Cheng, Jun, Ling, Qi, Wang, Jianguo, Guo, Haijun, Wei, Xuyong, Zheng, Shusen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311423/
https://ncbi.nlm.nih.gov/pubmed/25609232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0121-1
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