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Comprehensive genomic characterization of head and neck squamous cell carcinomas
The Cancer Genome Atlas profiled 279 head and neck squamous cell carcinomas (HNSCCs) to provide a comprehensive landscape of somatic genomic alterations. Here we show that human-papillomavirus-associated tumours are dominated by helical domain mutations of the oncogene PIK3CA, novel alterations invo...
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Publicado no: | Nature |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4311405/ https://ncbi.nlm.nih.gov/pubmed/25631445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14129 |
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