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Platelet-Derived Growth Factor: A Key Factor in the Pathogenesis of Graves' Ophthalmopathy and Potential Target for Treatment

Activation of orbital fibroblasts resulting in excessive proliferation, cytokine and hyaluronan production and differentiation into adipocytes, is a main determinant of orbital tissue inflammation and tissue expansion in Graves' ophthalmopathy (GO). During the last years we have shown that the...

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Detalles Bibliográficos
Publicado en:Eur Thyroid J
Autores principales: Virakul, Sita, van Steensel, Leendert, Dalm, Virgil A.S.H., Paridaens, Dion, van Hagen, P. Martin, Dik, Willem A.
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311307/
https://ncbi.nlm.nih.gov/pubmed/25759797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000367968
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