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Prediction of partition coefficient of some 3-hydroxy pyridine-4-one derivatives using combined partial least square regression and genetic algorithm

A quantiatative structure property relationship (QSPR) treatment was used to a data set consisting of diverse 3-hydroxypyridine-4-one derivatives to relate the logarithmic function of octanol:water partition coefficients (denoted by log p(o/w)) with theoretical molecular descriptors. Evaluation of a...

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Detalhes bibliográficos
Publicado no:Res Pharm Sci
Main Authors: Shahlaei, M., Fassihi, A., Saghaie, L., Zare, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311292/
https://ncbi.nlm.nih.gov/pubmed/25657783
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