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Rotenone Induces Cell Death of Cholinergic Neurons in an Organotypic Co-Culture Brain Slice Model

In Alzheimer and Parkinson’s disease cell death of cholinergic and dopaminergic neurons are characteristic hallmarks, respectively. It is well established that rotenone, an inhibitor of complex I of the electron transport chain, induces cell death of dopaminergic neurons, however, not much is known...

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Publicat a:Neurochem Res
Autors principals: Ullrich, Celine, Humpel, Christian
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311144/
https://ncbi.nlm.nih.gov/pubmed/19495971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-009-0014-9
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