Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor.

Histrionicotoxin from the Colombian frog Dendrobates histrionicus and its perhydro derivative reversibly block the acetylcholine-sensitive ion conductance system in frog neuromuscular preparations. The perhydro derivative and [3H]perhydrohistrionicotoxin, like histrionicotoxin, caused a significant...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Eldefrawi, A T, Eldefrawi, M E, Albuquerque, E X, Oliveira, A C, Mansour, N, Adler, M, Daly, J W, Brown, G B, Burgermeister, W, Witkop, B
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1977
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431098/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/301278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.5.2172
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