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Nature of the antigenic complex recognized by T lymphocytes: specific sensitization by antigens associated with allogeneic macrophages.

Alloreactive guinea pig thymus-derived (T) cells generated in vitro were rendered unresponsive to allogeneic macrophages by treatment with bromodeoxyuridine and light. The remaining T cells were subsequently primed and rechallenged in tissue culture with trinitrophenyl (Tnp)-modified syngeneic or al...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Thomas, D W, Shevach, E M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1977
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431083/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/68474/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.5.2104
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