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Trajectories of physiological dysregulation predicts mortality and health outcomes in a consistent manner across three populations

Mechanistic and evolutionary perspectives both agree that aging involves multiple integrated biochemical networks in the organism. In particular, the homeostatic physiological dysregulation (PD) hypothesis contends that aging is caused by the progressive breakdown of key regulatory processes. Howeve...

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Detalhes bibliográficos
Publicado no:Mech Ageing Dev
Main Authors: Milot, Emmanuel, Morissette-Thomas, V., Li, Qing, Fried, Linda P., Ferrucci, Luigi, Cohen, Alan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310774/
https://ncbi.nlm.nih.gov/pubmed/25454986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2014.10.001
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