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Trajectories of physiological dysregulation predicts mortality and health outcomes in a consistent manner across three populations

Mechanistic and evolutionary perspectives both agree that aging involves multiple integrated biochemical networks in the organism. In particular, the homeostatic physiological dysregulation (PD) hypothesis contends that aging is caused by the progressive breakdown of key regulatory processes. Howeve...

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Podrobná bibliografie
Vydáno v:Mech Ageing Dev
Hlavní autoři: Milot, Emmanuel, Morissette-Thomas, V., Li, Qing, Fried, Linda P., Ferrucci, Luigi, Cohen, Alan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310774/
https://ncbi.nlm.nih.gov/pubmed/25454986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2014.10.001
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