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Trajectories of physiological dysregulation predicts mortality and health outcomes in a consistent manner across three populations

Mechanistic and evolutionary perspectives both agree that aging involves multiple integrated biochemical networks in the organism. In particular, the homeostatic physiological dysregulation (PD) hypothesis contends that aging is caused by the progressive breakdown of key regulatory processes. Howeve...

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Pubblicato in:Mech Ageing Dev
Autori principali: Milot, Emmanuel, Morissette-Thomas, V., Li, Qing, Fried, Linda P., Ferrucci, Luigi, Cohen, Alan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310774/
https://ncbi.nlm.nih.gov/pubmed/25454986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2014.10.001
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