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Macrophages phagocytose nonopsonized silica particles using a unique microtubule-dependent pathway

Silica inhalation leads to the development of the chronic lung disease silicosis. Macrophages are killed by uptake of nonopsonized silica particles, and this is believed to play a critical role in the etiology of silicosis. However, the mechanism of nonopsonized-particle uptake is not well understoo...

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Bibliografische gegevens
Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Gilberti, Renée M., Knecht, David A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310742/
https://ncbi.nlm.nih.gov/pubmed/25428990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1301
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