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A Potential Role for Mechanical Forces in the Detachment of Podocytes and the Progression of CKD
Loss of podocytes underlies progression of CKD. Detachment of podocytes from the glomerular basement membrane (GBM) rather than apoptosis or necrosis seems to be the major mechanism of podocyte loss. Such detachment of viable podocytes may be caused by increased mechanical distending and shear force...
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| Publicado no: | J Am Soc Nephrol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310663/ https://ncbi.nlm.nih.gov/pubmed/25060060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014030278 |
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