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Phosphohexosyl components of a lysosomal enzyme are recognized by pinocytosis receptors on human fibroblasts.

Human beta-glucuronidase (beta-D-glucuronide glucuronosohydrolase, EC 3.2.1.31), like many other glycoprotein lysosomal hydrolases, is specifically taken up from the culture medium by human fibroblasts. Prior work has indicated that the enzyme exhibits charge heterogeneity and that "high-uptake" for...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kaplan, A, Achord, D T, Sly, W S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431066/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/266721/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.5.2026
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