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Enhancing Allosteric Inhibition in Thermus thermophilus Phosphofructokinase

[Image: see text] The coupling between the binding of the substrate Fru-6-P and the inhibitor phospho(enol)pyruvate (PEP) in phosphofructokinase (PFK) from the extreme thermophile Thermus thermophilus is much weaker than that seen in a PFK from Bacillus stearothermophilus. From the crystal structure...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: McGresham, Maria S., Reinhart, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310622/
https://ncbi.nlm.nih.gov/pubmed/25531642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501127a
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