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Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingosine-1-Phosphate Pathway

Nephrokeli (NPKL) is a Chinese herbal formula that has been used to treat patients with IgA nephropathy (IgAN) for improvement of proteinuria and kidney injury. However, the mechanism remains unclear. Sphingosine-1-phosphate (S1P) and its receptors S1PR2 and S1PR3 are known to play an important role...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhong, Yifei, Wang, Ke, Zhang, Xianwen, Cai, Xiaofan, Chen, Yiping, Deng, Yueyi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310606/
https://ncbi.nlm.nih.gov/pubmed/25633986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116873
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