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Rapamycin Improves Palmitate-Induced ER Stress/NFκB Pathways Associated with Stimulating Autophagy in Adipocytes

Obesity-induced endoplasmic reticulum (ER) stress and inflammation lead to adipocytes dysfunction. Autophagy helps to adapt to cellular stress and involves in regulating innate inflammatory response. In present study, we examined the activity of rapamycin, a mTOR kinase inhibitor, against endoplasmi...

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Bibliografische gegevens
Gepubliceerd in:Mediators Inflamm
Hoofdauteurs: Yin, Jiajing, Gu, Liping, Wang, Yufan, Fan, Nengguang, Ma, Yuhang, Peng, Yongde
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310475/
https://ncbi.nlm.nih.gov/pubmed/25653476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/272313
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