Rapamycin Improves Palmitate-Induced ER Stress/NFκB Pathways Associated with Stimulating Autophagy in Adipocytes

Obesity-induced endoplasmic reticulum (ER) stress and inflammation lead to adipocytes dysfunction. Autophagy helps to adapt to cellular stress and involves in regulating innate inflammatory response. In present study, we examined the activity of rapamycin, a mTOR kinase inhibitor, against endoplasmi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mediators Inflamm
Main Authors: Yin, Jiajing, Gu, Liping, Wang, Yufan, Fan, Nengguang, Ma, Yuhang, Peng, Yongde
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310475/
https://ncbi.nlm.nih.gov/pubmed/25653476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/272313
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