Rapamycin Improves Palmitate-Induced ER Stress/NFκB Pathways Associated with Stimulating Autophagy in Adipocytes

Obesity-induced endoplasmic reticulum (ER) stress and inflammation lead to adipocytes dysfunction. Autophagy helps to adapt to cellular stress and involves in regulating innate inflammatory response. In present study, we examined the activity of rapamycin, a mTOR kinase inhibitor, against endoplasmi...

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Vydáno v:Mediators Inflamm
Hlavní autoři: Yin, Jiajing, Gu, Liping, Wang, Yufan, Fan, Nengguang, Ma, Yuhang, Peng, Yongde
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310475/
https://ncbi.nlm.nih.gov/pubmed/25653476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/272313
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