Rapamycin Improves Palmitate-Induced ER Stress/NFκB Pathways Associated with Stimulating Autophagy in Adipocytes

Obesity-induced endoplasmic reticulum (ER) stress and inflammation lead to adipocytes dysfunction. Autophagy helps to adapt to cellular stress and involves in regulating innate inflammatory response. In present study, we examined the activity of rapamycin, a mTOR kinase inhibitor, against endoplasmi...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Yin, Jiajing, Gu, Liping, Wang, Yufan, Fan, Nengguang, Ma, Yuhang, Peng, Yongde
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310475/
https://ncbi.nlm.nih.gov/pubmed/25653476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/272313
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