Activation of Endothelial Transient Receptor Potential C3 Channel Is Required for Small Conductance Calcium‐Activated Potassium Channel Activation and Sustained Endothelial Hyperpolarization and Vasodilation of Cerebral Artery

BACKGROUND: Transient receptor potential C3 (TRPC3) has been demonstrated to be involved in the regulation of vascular tone through endothelial cell (EC) hyperpolarization and endothelium‐dependent hyperpolarization–mediated vasodilation. However, the mechanism by which TRPC3 regulates these process...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Kochukov, Mikhail Y., Balasubramanian, Adithya, Abramowitz, Joel, Birnbaumer, Lutz, Marrelli, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310376/
https://ncbi.nlm.nih.gov/pubmed/25142058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000913
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