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Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models

Patient-derived human-in-mouse xenograft models of breast cancer (PDX models) that exhibit spontaneous lung metastases offer a potentially powerful model of cancer metastasis. In this study, we evaluated the malignant character of lung micro-metastases that emerge in such models after orthotopic imp...

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Detalles Bibliográficos
Publicado en:Cancer Res
Main Authors: Bockhorn, Jessica, Prat, Aleix, Chang, Ya-Fang, Liu, Xia, Huang, Simo, Shang, Meng, Nwachukwu, Chika, Gomez-Vega, Maria J., Harrell, J. Chuck, Olopade, Olufunmilayo I., Perou, Charles M., Liu, Huiping
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310213/
https://ncbi.nlm.nih.gov/pubmed/25339353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1188
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