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Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs.

In the myenteric plexus-longitudinal muscle bioassay, beta-endorphin, i.e., beta-lipotropin (beta-LPH)-[61-91], has a potency of 450 with confidence limits of 281-966 when Met5-enkephalin is used as a reference standard with a potency of 100. The primary amide and the ethylamide of Met5-enkephalin h...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ling, N, Guillemin, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1976
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431021/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1067621/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.9.3308
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