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Rational selection of experimental readout and intervention sites for reducing uncertainties in computational model predictions

BACKGROUND: Understanding the dynamics of biological processes can substantially be supported by computational models in the form of nonlinear ordinary differential equations (ODE). Typically, this model class contains many unknown parameters, which are estimated from inadequate and noisy data. Depe...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Flassig, Robert J, Migal, Iryna, der Zalm, Esther van, Rihko-Struckmann, Liisa, Sundmacher, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310145/
https://ncbi.nlm.nih.gov/pubmed/25592474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-014-0436-5
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