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Reduced T-cell repertoire restrictions in abatacept-treated rheumatoid arthritis patients
BACKGROUND: CD28(neg) T cells, which display functional characteristic of oligoclonally expanded cytotoxic memory T lymphocytes, are believed to be pathologically relevant in rheumatoid arthritis manifestation. The CD28 co-stimulation blockade by abatacept can prevent the generation of CD28(neg) T-c...
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310138/ https://ncbi.nlm.nih.gov/pubmed/25592982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0363-2 |
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