In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver

BACKGROUND: Maternal smoking is one of the most important modifiable risk factors for low birthweight, which is strongly associated with increased cardiometabolic disease risk in adulthood. Maternal smoking reduces the levels of the methyl donor vitamin B12 and is associated with altered DNA methyla...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Drake, Amanda J, O’Shaughnessy, Peter J, Bhattacharya, Siladitya, Monteiro, Ana, Kerrigan, David, Goetz, Sven, Raab, Andrea, Rhind, Stewart M, Sinclair, Kevin D, Meharg, Andrew A, Feldmann, Jörg, Fowler, Paul A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310040/
https://ncbi.nlm.nih.gov/pubmed/25630355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-014-0251-x
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