Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson’s disease models are mediated by GPR109A-dependent mechanisms

BACKGROUND: Accumulating evidence suggests that neuroinflammation plays an important role in the progression of Parkinson’s disease (PD). Excessively activated microglia produce several pro-inflammatory enzymes and pro-inflammatory cytokines, leading to damage to surrounding neurons and eventually i...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Fu, Shou-Peng, Wang, Jian-Fa, Xue, Wen-Jing, Liu, Hong-Mei, Liu, Bing-run, Zeng, Ya-Long, Li, Su-Nan, Huang, Bing-Xu, Lv, Qing-Kang, Wang, Wei, Liu, Ju-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310035/
https://ncbi.nlm.nih.gov/pubmed/25595674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0230-3
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