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Development and Characterization of Mixed Niosomes for Oral Delivery Using Candesartan Cilexetil as a Model Poorly Water-Soluble Drug

The aim of this study was to prepare candesartan cilexetil-loaded niosomes and mixed niosomes to enhance the aqueous solubility of the drug, thus improving its oral bioavailability. The formulations were prepared using various types and combinations of surfactants, copolymers, and charge-inducing ag...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Sezgin-Bayindir, Zerrin, Antep, Mustafa Naim, Yuksel, Nilufer
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309817/
https://ncbi.nlm.nih.gov/pubmed/25204859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0213-9
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