Model Drug as Pore Former for Controlled Release of Water-Soluble Metoprolol Succinate from Ethylcellulose-Coated Pellets Without Lag Phase: Opportunities and Challenges

The objective of the present study was to evaluate the feasibility of using model drug metoprolol succinate (MS) as a pore former to modify the initial lag phase (i.e., a slow or non-release phase in the first 1–2 h) associated with the drug release from coated pellets. MS-layered cores with high dr...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:AAPS PharmSciTech
Asıl Yazarlar: Wang, Yuli, Dai, Jingjing, Chang, Xinyi, Yang, Meiyan, Shen, Ruifang, Shan, Li, Qian, Yong, Gao, Chunsheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309812/
https://ncbi.nlm.nih.gov/pubmed/25163432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0197-5
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