Angiotensin Converting Enzyme Inhibitors (ACEI) and doxorubicin pharmacokinetics in women receiving adjuvant breast cancer treatment

PURPOSE: Doxorubicin (DOX) chemotherapy can cause cardiac complications. Angiotensin converting enzyme inhibitors (ACEI) may protect against these complications. We performed a pharmacokinetics (PK) study to determine whether DOX levels are altered in the presence of ACEI. METHODS: In this randomize...

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Опубликовано в: :Springerplus
Главные авторы: Blaes, Anne, Duprez, Daniel, Defor, Todd, Shanley, Ryan, Beckwith, Heather, Haddad, Tufia, Potter, David, Yee, Douglas, Sanghavi, Kinjal, Jacobson, Pamala
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2015
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309801/
https://ncbi.nlm.nih.gov/pubmed/25646154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-0802-4
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