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Tolerance and dependence evoked by an endogenous opiate peptide.

Incubation of neuroblastoma X glioma hybrid cells for 12-97 hr with methionine-enkephalin results in an increase in adenylate cyclase activity [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] that is mediated by the opiate receptor. The results show that cells become tolerant to, and dependent upon...

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Hlavní autoři: Lampert, A, Nirenberg, M, Klee, W A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1976
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC430968/
https://ncbi.nlm.nih.gov/pubmed/1067610
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