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Addressing phenoconversion: the Achilles' heel of personalized medicine
Phenoconversion is a phenomenon that converts genotypic extensive metabolizers (EMs) into phenotypic poor metabolizers (PMs) of drugs, thereby modifying their clinical response to that of genotypic PMs. Phenoconversion, usually resulting from nongenetic extrinsic factors, has a significant impact on...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309629/ https://ncbi.nlm.nih.gov/pubmed/24913012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12441 |
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