Low Prevalence of CHEK2 Gene Mutations in Multiethnic Cohorts of Breast Cancer Patients in Malaysia

CHEK2 is a protein kinase that is involved in cell-cycle checkpoint control after DNA damage. Germline mutations in CHEK2 gene have been associated with increase in breast cancer risk. The aim of this study is to identify the CHEK2 gene germline mutations among high-risk breast cancer patients and i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mohamad, Suriati, Isa, Nurismah Md, Muhammad, Rohaizak, Emran, Nor Aina, Kitan, Nor Mayah, Kang, Peter, Kang, In Nee, Taib, Nur Aishah Mohd, Teo, Soo Hwang, Akmal, Sharifah Noor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309602/
https://ncbi.nlm.nih.gov/pubmed/25629968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117104
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