Genetic Variants Modulating CRIPTO Serum Levels Identified by Genome-Wide Association Study in Cilento Isolates

Cripto, the founding member of the EGF-CFC genes, plays an essential role in embryo development and is involved in cancer progression. Cripto is a GPI-anchored protein that can interact with various components of multiple signaling pathways, such as TGF-β, Wnt and MAPK, driving different processes,...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Ruggiero, Daniela, Nappo, Stefania, Nutile, Teresa, Sorice, Rossella, Talotta, Francesco, Giorgio, Emilia, Bellenguez, Celine, Leutenegger, Anne-Louise, Liguori, Giovanna L., Ciullo, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309561/
https://ncbi.nlm.nih.gov/pubmed/25629528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004976
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