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Conservation and Immunogenicity of Novel Antigens in Diverse Isolates of Enterotoxigenic Escherichia coli

BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) are common causes of diarrheal morbidity and mortality in developing countries for which there is currently no vaccine. Heterogeneity in classical ETEC antigens known as colonization factors (CFs) and poor efficacy of toxoid-based approaches to dat...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Negl Trop Dis
Hauptverfasser: Luo, Qingwei, Qadri, Firdausi, Kansal, Rita, Rasko, David A., Sheikh, Alaullah, Fleckenstein, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309559/
https://ncbi.nlm.nih.gov/pubmed/25629897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003446
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