Long-Term Use of the Thrombopoietin-Mimetic Romiplostim in Children With Severe Chronic Immune Thrombocytopenia (ITP)

BACKGROUND: Treatment of chronic severe pediatric ITP is not well studied. In a phase 1/2 12–16-week study, 15/17 romiplostim-treated patients achieved platelet counts ≥50 × 10(9)/L, and romiplostim treatment was well tolerated. In a subsequent open-label extension (≤109 weeks), 20/22 patients recei...

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Vydáno v:Pediatr Blood Cancer
Hlavní autoři: Bussel, James B, Hsieh, Loan, Buchanan, George R, Stine, Kimo, Kalpatthi, Ram, Gnarra, David J, Ho, Richard H, Nie, Kun, Eisen, Melissa
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309514/
https://ncbi.nlm.nih.gov/pubmed/25345874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25136
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