Different Degrees of NADPH Oxidase 2 Regulation and In Vivo Platelet Activation: Lesson From Chronic Granulomatous Disease

BACKGROUND: In vitro study showed that NADPH oxidase (NOx), the most important enzyme producing reactive oxygen species (ROS), plays a role in the process of platelet activation. However, it is unclear if changes in its activity affect platelet activation in vivo. METHODS AND RESULTS: In vivo and ex...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Carnevale, Roberto, Loffredo, Lorenzo, Sanguigni, Valerio, Plebani, Alessandro, Rossi, Paolo, Pignata, Claudio, Martire, Baldassarre, Finocchi, Andrea, Pietrogrande, Maria Cristina, Azzari, Chiara, Soresina, Anna Rosa, Martino, Silvana, Cirillo, Emilia, Martino, Francesco, Pignatelli, Pasquale, Violi, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309093/
https://ncbi.nlm.nih.gov/pubmed/24973227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000920
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