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Mechanistic Insights into a Classic Wonder Drug—Aspirin
[Image: see text] Aspirin, one of the oldest and most common anti-inflammatory agents, has recently been shown to reduce cancer risks. The principal pharmacological effects of aspirin are known to arise from its covalent modification of cyclooxygenase-2 (COX-2) through acetylation of Ser530, but the...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309031/ https://ncbi.nlm.nih.gov/pubmed/25514511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5112964 |
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