A crossover randomized comparative study of zofenopril and ramipril on cough reflex and airway inflammation in healthy volunteers

BACKGROUND: Persistent dry cough is a well known unwanted effect of Angiotensin-Converting Enzyme inhibitors (ACE-i). Animal studies have shown that the ACE-i zofenopril has a less tussigenic effect compared to the widely used ACE-i ramipril. The aim of this study was to compare cough sensitivity to...

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Publicado en:Cough
Autores principales: Lavorini, Federico, Chellini, Elisa, Innocenti, Margherita, Campi, Giacomo, Egan, Colin Gerard, Mogavero, Selene, Fontana, Giovanni A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308941/
https://ncbi.nlm.nih.gov/pubmed/25632296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12997-014-0007-5
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