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Application of imidazole as a selective inhibitor thromboxane synthetase in human platelets.

Human platelet suspensions release a rabbit-aorta-contracting substance (previously identified as thromboxane A2) during aggregation produced by arachidonic acid, prostaglandin endoperoxide, thrombin, and collagen. Incubation of platelets with imidazole did not interfere with the aggregation produce...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Needleman, P, Raz, A, Ferrendelli, J A, Minkes, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1977
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430864/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/193113/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.4.1716
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