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The role of membrane curvature elastic stress for function of rhodopsin-like G protein-coupled receptors

The human genome encodes about 800 different G protein-coupled receptors (GPCR). They are key molecules in signal transduction pathways that transmit signals of a variety of ligands such as hormones and neurotransmitters to the cell interior. Upon ligand binding, the receptors undergo structural tra...

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Bibliografiske detaljer
Udgivet i:Biochimie
Main Authors: Soubias, Olivier, Teague, Walter E., Hines, Kirk G., Gawrisch, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308488/
https://ncbi.nlm.nih.gov/pubmed/25447139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2014.10.011
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