Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays

BACKGROUND: Low molecular weight heparins (LMWH’s) are used to prevent and treat thrombosis. Tests for monitoring LMWH’s include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH’s varying affinities fo...

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Publicado en:PLoS One
Autores principales: Thomas, Owain, Lybeck, Emanuel, Strandberg, Karin, Tynngård, Nahreen, Schött, Ulf
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308107/
https://ncbi.nlm.nih.gov/pubmed/25625201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116835
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