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Exact reconstruction of gene regulatory networks using compressive sensing

BACKGROUND: We consider the problem of reconstructing a gene regulatory network structure from limited time series gene expression data, without any a priori knowledge of connectivity. We assume that the network is sparse, meaning the connectivity among genes is much less than full connectivity. We...

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Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Chang, Young Hwan, Gray, Joe W, Tomlin, Claire J
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308013/
https://ncbi.nlm.nih.gov/pubmed/25495633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-014-0400-4
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