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Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes

Neural electrodes are an important part of brain-machine interface devices that can restore functionality to patients with sensory and movement disorders. Chronically implanted neural electrodes induce an unfavorable tissue response which includes inflammation, scar formation, and neuronal cell deat...

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Bibliographic Details
Published in:Biomaterials
Main Authors: Gutowski, Stacie M., Shoemaker, James T., Templeman, Kellie L., Wei, Yang, Latour, Robert A., Bellamkonda, Ravi V., LaPlaca, Michelle C., García, Andrés J.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307944/
https://ncbi.nlm.nih.gov/pubmed/25617126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.12.009
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