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Effects of food and alcohol on the pharmacokinetics of an oral, extended-release formulation of hydrocodone in healthy volunteers

BACKGROUND: The purpose of this study was to evaluate the pharmacokinetics, bioavailability, and safety of oral extended-release hydrocodone (HC-ER) when administered with food or alcohol. METHODS: Two single-center, open-label, randomized, crossover studies were conducted in healthy volunteers. In...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol
Main Authors: Farr, Stephen J, Robinson, Cynthia Y, Rubino, Christopher M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307648/
https://ncbi.nlm.nih.gov/pubmed/25653563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S70831
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