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Profiling of Ubiquitination Pathway Genes in Peripheral Cells from Patients with Frontotemporal Dementia due to C9ORF72 and GRN Mutations

We analysed the expression levels of 84 key genes involved in the regulated degradation of cellular protein by the ubiquitin-proteasome system in peripheral cells from patients with frontotemporal dementia (FTD) due to C9ORF72 and GRN mutations, as compared with sporadic FTD and age-matched controls...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Serpente, Maria, Fenoglio, Chiara, Cioffi, Sara M. G., Bonsi, Rossana, Arighi, Andrea, Fumagalli, Giorgio G., Ghezzi, Laura, Scarpini, Elio, Galimberti, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307308/
https://ncbi.nlm.nih.gov/pubmed/25580532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16011385
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