Comparison of regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma cells grown in vivo and in vitro.

Unlike the normal liver, numerous transplantable rodent and human hepatomas are unable to alter their rate of sterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-GoA) reductase [mevalonate: NADP+ oxidoreductase (CoA-acylating), EC 1.1.1.34] activity in response to a dietary cholesterol c...

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Bibliographic Details
Main Authors: Beirne, O R, Watson, J A
Format: Artigo
Language:Inglês
Published: 1976
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC430723/
https://ncbi.nlm.nih.gov/pubmed/183207
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