Platinum binds selectively to phosphorothioate groups in mono- and polynucleotides: a general method for heavy metal staining of specific nucleotides.

Platinum binding to nucleoside phosphorothioates has been examined to determine their suitability as heavy metal labeling sites for the potential electron microscopic sequencing of nucleic acids. The complex platinum terpyridine nitrate forms a 1:1 adduct with either adenosine or uridine monophospho...

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Main Authors: Strothkamp, K G, Lippard, S J
Format: Artigo
Sprog:Inglês
Udgivet: 1976
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC430681/
https://ncbi.nlm.nih.gov/pubmed/60759
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