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AHR2-Mediated Transcriptomic Responses Underlying the Synergistic Cardiac Developmental Toxicity of PAHs

Polycyclic aromatic hydrocarbons (PAHs) induce developmental defects including cardiac deformities in fish. The aryl hydrocarbon receptor (AHR) mediates the toxicity of some PAHs. Exposure to a simple PAH mixture during embryo development consisting of an AHR agonist (benzo(a)pyrene-BaP) with fluora...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Jayasundara, Nishad, Van Tiem Garner, Lindsey, Meyer, Joel N., Erwin, Kyle N., Di Giulio, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306723/
https://ncbi.nlm.nih.gov/pubmed/25412620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu245
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