Ethylphenacemide and phenacemide: conformational similarities to diphenylhydantoin and stereochemical basis of anticonvulsant activity.
The three-dimensional molecular structures of the potent anticonvulsant agents phenacemide and ethylphenacemide have been determined by single-crystal x-ray diffraction. Although these compounds possess straight-chain acetylurea groupings, in the crystalline state both molecules adopt a pseudocyclic...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1977
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430664/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/265568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.3.1264 |
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