Src and Caveolin-1 reciprocally regulate metastasis via a common downstream signaling pathway in bladder cancer

In bladder cancer, increased Caveolin-1 (Cav-1) expression and decreased Src expression and kinase activity correlate with tumor aggressiveness. Here, we investigate the clinical and functional significance if any, of this reciprocal expression in bladder cancer metastasis. We evaluated the ability...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Thomas, Shibu, Overdevest, Jonathan B., Nitz, Matthew D., Williams, Paul D., Owens, Charles R., Sanchez-Carbayo, Marta, Frierson, Henry F., Schwartz, Martin A., Theodorescu, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306590/
https://ncbi.nlm.nih.gov/pubmed/21148751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0730
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