The Lyme disease agent exploits a tick protein to infect the mammalian host

The Lyme disease agent, Borrelia burgdorferi, is maintained in a tick–mouse cycle(1,2).Here we show that B. burgdorferi usurps a tick salivary protein, Salp15 (ref. 3), to facilitate the infection of mice. The level of salp15 expression was selectively enhanced by the presence of B. burgdorferi in I...

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Bibliografiske detaljer
Udgivet i:	Nature
Main Authors:	Ramamoorthi, Nandhini, Narasimhan, Sukanya, Pal, Utpal, Bao, Fukai, Yang, Xiaofeng F., Fish, Durland, Anguita, Juan, Norgard, Michael V., Kantor, Fred S., Anderson, John F., Koski, Raymond A., Fikrig, Erol
Format:	Artigo
Sprog:	Inglês
Udgivet:	2005
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4306560/ https://ncbi.nlm.nih.gov/pubmed/16049492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03812
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The Lyme disease agent exploits a tick protein to infect the mammalian host

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