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Human in vitro skin organ culture as a model system for evaluating DNA repair

BACKGROUND: UV-exposures result in accumulation of genetic lesions that facilitate the development of skin cancer. Numerous pharmacologic agents are currently under development to both inhibit formation of DNA lesions and enhance repair. Drugs must be evaluated in vitro, currently performed in cell...

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Detalhes bibliográficos
Publicado no:J Dermatol Sci
Main Authors: Liu, Hannah, Tuchinda, Papapit, Fishelevich, Rita, Harberts, Erin, Gaspari, Anthony A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306456/
https://ncbi.nlm.nih.gov/pubmed/24636351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2014.02.003
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