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Elucidating the exact role of engineered CRABPII residues for the formation of a retinal protonated Schiff base
Cellular Retinoic Acid Binding Protein II (CRABPII) has been re-engineered to specifically bind and react with all–trans-retinal to form a protonated Schiff base. Each step of this process has been dissected and four residues (Lys132, Tyr134, Arg111, Glu121) within the CRABPII binding site have been...
Shranjeno v:
| izdano v: | Proteins |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4306427/ https://ncbi.nlm.nih.gov/pubmed/19603486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22495 |
| Oznake: |
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