Dose Response of Endotoxin on Hepatocyte and Muscle Mitochondrial Respiration In Vitro

Introduction. Results on mitochondrial dysfunction in sepsis are controversial. We aimed to assess effects of LPS at wide dose and time ranges on hepatocytes and isolated skeletal muscle mitochondria. Methods. Human hepatocellular carcinoma cells (HepG2) were exposed to placebo or LPS (0.1, 1, and 1...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biomed Res Int
Auteurs principaux: Jeger, Victor, Brandt, Sebastian, Porta, Francesca, Jakob, Stephan M., Takala, Jukka, Djafarzadeh, Siamak
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306363/
https://ncbi.nlm.nih.gov/pubmed/25649304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/353074
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