Dose Response of Endotoxin on Hepatocyte and Muscle Mitochondrial Respiration In Vitro

Introduction. Results on mitochondrial dysfunction in sepsis are controversial. We aimed to assess effects of LPS at wide dose and time ranges on hepatocytes and isolated skeletal muscle mitochondria. Methods. Human hepatocellular carcinoma cells (HepG2) were exposed to placebo or LPS (0.1, 1, and 1...

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Vydáno v:Biomed Res Int
Hlavní autoři: Jeger, Victor, Brandt, Sebastian, Porta, Francesca, Jakob, Stephan M., Takala, Jukka, Djafarzadeh, Siamak
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306363/
https://ncbi.nlm.nih.gov/pubmed/25649304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/353074
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