Dose Response of Endotoxin on Hepatocyte and Muscle Mitochondrial Respiration In Vitro

Introduction. Results on mitochondrial dysfunction in sepsis are controversial. We aimed to assess effects of LPS at wide dose and time ranges on hepatocytes and isolated skeletal muscle mitochondria. Methods. Human hepatocellular carcinoma cells (HepG2) were exposed to placebo or LPS (0.1, 1, and 1...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Jeger, Victor, Brandt, Sebastian, Porta, Francesca, Jakob, Stephan M., Takala, Jukka, Djafarzadeh, Siamak
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306363/
https://ncbi.nlm.nih.gov/pubmed/25649304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/353074
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