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Bevacizumab plus Ipilimumab in Patients with Metastatic Melanoma

Ipilimumab improves survival in advanced melanoma and can induce immune-mediated tumor vasculopathy. Besides promoting angiogenesis, vascular endothelial growth factor (VEGF) suppresses dendritic cell maturation and modulates lymphocyte endothelial trafficking. This study investigated the combinatio...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Hodi, F. Stephen, Lawrence, Donald, Lezcano, Cecilia, Wu, Xinqi, Zhou, Jun, Sasada, Tetsuro, Zeng, Wanyong, Giobbie-Hurder, Anita, Atkins, Michael B., Ibrahim, Nageatte, Friedlander, Philip, Flaherty, Keith T., Murphy, George F., Rodig, Scott, Velazquez, Elsa F., Mihm, Martin C., Russell, Sara, Dipiro, Pamela, Yap, Jeffrey T., Ramaiya, Nikhil, Van den Abbeele, Annick D., Gargano, Maria, McDermott, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306338/
https://ncbi.nlm.nih.gov/pubmed/24838938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0053
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