Bevacizumab plus Ipilimumab in Patients with Metastatic Melanoma

Ipilimumab improves survival in advanced melanoma and can induce immune-mediated tumor vasculopathy. Besides promoting angiogenesis, vascular endothelial growth factor (VEGF) suppresses dendritic cell maturation and modulates lymphocyte endothelial trafficking. This study investigated the combinatio...

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Publicat a:Cancer Immunol Res
Autors principals: Hodi, F. Stephen, Lawrence, Donald, Lezcano, Cecilia, Wu, Xinqi, Zhou, Jun, Sasada, Tetsuro, Zeng, Wanyong, Giobbie-Hurder, Anita, Atkins, Michael B., Ibrahim, Nageatte, Friedlander, Philip, Flaherty, Keith T., Murphy, George F., Rodig, Scott, Velazquez, Elsa F., Mihm, Martin C., Russell, Sara, Dipiro, Pamela, Yap, Jeffrey T., Ramaiya, Nikhil, Van den Abbeele, Annick D., Gargano, Maria, McDermott, David
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306338/
https://ncbi.nlm.nih.gov/pubmed/24838938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0053
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